Flow-Gradient Patterns in Severe Aortic Stenosis with Preserved Ejection Fraction: Clinical Characteristics and Predictors of Survival

نویسندگان

  • Mackram F. Eleid
  • Paul Sorajja
  • Hector I. Michelena
  • Joseph F. Malouf
  • Christopher G. Scott
  • Patricia A. Pellikka
چکیده

Ad Ad Addr dr dres es ess s s fo fo for r r Co Co Corr rr rres es espo po pond nd nden en ence ce ce: : : Abstract: Background—Among patients with severe aortic stenosis (AS) and preserved ejection fraction

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Response to letter regarding article, "Flow-gradient patterns in severe aortic stenosis with preserved ejection fraction: clinical characteristics and predictors of survival".

BACKGROUND Among patients with severe aortic stenosis (AS) and preserved ejection fraction, those with low gradient (LG) and reduced stroke volume may have an adverse prognosis. We investigated the prognostic impact of stroke volume using the recently proposed flow-gradient classification. METHODS AND RESULTS We examined 1704 consecutive patients with severe AS (aortic valve area <1.0 cm(2)) ...

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BACKGROUND Recent studies and current clinical observations suggest that some patients with severe aortic stenosis on the basis of aortic valve area may paradoxically have a relatively low gradient despite the presence of a preserved left ventricular (LV) ejection fraction. The objective of the present study was to document the prevalence, potential mechanisms, and clinical relevance of this ph...

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Low-flow aortic stenosis and preserved left ventricular ejection fraction.

Valvular aortic stenosis (AS) is the most frequent valvular disease in developed countries. Treatment decisions in AS are mainly based upon the symptomatic status of the patient and the severity of AS. Doppler echocardiography represents the standard tool for detecting and assessing the severity of the disease. Under the same denomination of severe AS [aortic valve area (AVA) < 1 cm(2)], severa...

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Paradoxical low flow and/or low gradient severe aortic stenosis despite preserved left ventricular ejection fraction: implications for diagnosis and treatment

Paradoxical low flow, low gradient, severe aortic stenosis (AS) despite preserved ejection fraction is a recently described clinical entity whereby patients with severe AS on the basis of aortic valve area have a lower than expected gradient in relation to generally accepted values. This mode of presentation of severe AS is relatively frequent (up to 35% of cases) and such patients have a clust...

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تاریخ انتشار 2013